Joint effects of pregnancy, sociocultural, and environmental factors on early life gut microbiome structure and diversity.
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ABSTRACT:
SUBMITTER: Levin AM
PROVIDER: S-EPMC4997337 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Publications
Joint effects of pregnancy, sociocultural, and environmental factors on early life gut microbiome structure and diversity.
Levin Albert M AM Sitarik Alexandra R AR Havstad Suzanne L SL Fujimura Kei E KE Wegienka Ganesa G Cassidy-Bushrow Andrea E AE Kim Haejin H Zoratti Edward M EM Lukacs Nicholas W NW Boushey Homer A HA Ownby Dennis R DR Lynch Susan V SV Johnson Christine C CC
Scientific reports 20160825
The joint impact of pregnancy, environmental, and sociocultural exposures on early life gut microbiome is not yet well-characterized, especially in racially and socioeconomically diverse populations. Gut microbiota of 298 children from a Detroit-based birth cohort were profiled using 16S rRNA sequencing: 130 neonates (median age = 1.2 months) and 168 infants (median age = 6.6 months). Multiple factors were associated with neonatal gut microbiome composition in both single- and multi-factor model ...[more]
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