Anticancer Platelet-Mimicking Nanovehicles.
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ABSTRACT:
SUBMITTER: Hu Q
PROVIDER: S-EPMC4998740 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Publications
Anticancer Platelet-Mimicking Nanovehicles.
Hu Quanyin Q Sun Wujin W Qian Chengen C Wang Chao C Bomba Hunter N HN Gu Zhen Z
Advanced materials (Deerfield Beach, Fla.) 20150929 44
A core-shell nanovehicle coated with a platelet membrane (PM) is developed for targeted and site-specific delivery of an extracellularly active drug and an intracellular functional small-molecular drug, leading to enhanced antitumor efficacy. This PM-coated nanovehicle can also effectively eliminate the circulating tumor cells in vivo and inhibit development of tumor metastasis. ...[more]
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