Ontology highlight
ABSTRACT:
SUBMITTER: Atay O
PROVIDER: S-EPMC5001915 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Atay Oguzhan O Doncic Andreas A Skotheim Jan M JM
Cell systems 20160721 2
Cellular decisions are made by complex networks that are difficult to analyze. Although it is common to analyze smaller sub-networks known as network motifs, it is unclear whether this is valid, because these motifs are embedded in complex larger networks. Here, we address the general question of modularity by examining the S. cerevisiae pheromone response. We demonstrate that the feedforward motif controlling the cell-cycle inhibitor Far1 is insulated from cell-cycle dynamics by the positive fe ...[more]