Unknown

Dataset Information

0

Novel Technique of Transepithelial Corneal Cross-Linking Using Iontophoresis in Progressive Keratoconus.


ABSTRACT: In this work, the authors presented the techniques and the preliminary results at 6 months of a randomized controlled trial (NCT02117999) comparing a novel transepithelial corneal cross-linking protocol using iontophoresis with the Dresden protocol for the treatment of progressive keratoconus. At 6 months, there was a significant average improvement with an average flattening of the maximum simulated keratometry reading of 0.72 ± 1.20?D (P = 0.01); in addition, corrected distance visual acuity improved significantly (P = 0.08) and spherical equivalent refraction was significantly less myopic (P = 0.02) 6 months after transepithelial corneal cross-linking with iontophoresis. The novel protocol using iontophoresis showed comparable results with standard corneal cross-linking to halt progression of keratoconus during 6-month follow-up. Investigation of the long-term RCT outcomes are ongoing to verify the efficacy of this transepithelial corneal cross-linking protocol and to determine if it may be comparable with standard corneal cross-linking in the management of progressive keratoconus.

SUBMITTER: Lombardo M 

PROVIDER: S-EPMC5002487 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

altmetric image

Publications

Novel Technique of Transepithelial Corneal Cross-Linking Using Iontophoresis in Progressive Keratoconus.

Lombardo Marco M   Serrao Sebastiano S   Raffa Paolo P   Rosati Marianna M   Lombardo Giuseppe G  

Journal of ophthalmology 20160815


In this work, the authors presented the techniques and the preliminary results at 6 months of a randomized controlled trial (NCT02117999) comparing a novel transepithelial corneal cross-linking protocol using iontophoresis with the Dresden protocol for the treatment of progressive keratoconus. At 6 months, there was a significant average improvement with an average flattening of the maximum simulated keratometry reading of 0.72 ± 1.20 D (P = 0.01); in addition, corrected distance visual acuity i  ...[more]

Similar Datasets

| S-EPMC5886478 | biostudies-literature
| S-EPMC6411486 | biostudies-literature
| S-EPMC8094622 | biostudies-literature
| S-EPMC7864754 | biostudies-literature
| S-EPMC8273905 | biostudies-literature
| S-EPMC5510105 | biostudies-other
| S-EPMC5485290 | biostudies-other
| S-EPMC5746954 | biostudies-literature
| S-EPMC5963884 | biostudies-literature
| S-EPMC6747657 | biostudies-literature