Exploring the feasibility of next-generation sequencing and microarray data meta-analysis.
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ABSTRACT:
SUBMITTER: Wu PY
PROVIDER: S-EPMC5003043 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
Exploring the feasibility of next-generation sequencing and microarray data meta-analysis.
Wu Po-Yen PY Phan John H JH Wang May D MD
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 20110101
Emerging next-generation sequencing (NGS) technology potentially resolves many issues that prevent widespread clinical use of gene expression microarrays. However, the number of publicly available NGS datasets is still smaller than that of microarrays. This paper explores the possibilities for combining information from both microarray and NGS gene expression datasets for the discovery of differentially expressed genes (DEGs). We evaluate several existing methods in detecting DEGs using individu ...[more]
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