Ontology highlight
ABSTRACT:
SUBMITTER: Ding Y
PROVIDER: S-EPMC5003635 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Ding Ye Y Ding Chunyong C Ye Na N Liu Zhiqing Z Wold Eric A EA Chen Haiying H Wild Christopher C Shen Qiang Q Zhou Jia J
European journal of medicinal chemistry 20160613
Natural products have historically been, and continue to be, an invaluable source for the discovery of various therapeutic agents. Oridonin, a natural diterpenoid widely applied in traditional Chinese medicines, exhibits a broad range of biological effects including anticancer and anti-inflammatory activities. To further improve its potency, aqueous solubility and bioavailability, the oridonin template serves as an exciting platform for drug discovery to yield better candidates with unique targe ...[more]