Ontology highlight
ABSTRACT:
SUBMITTER: Li P
PROVIDER: S-EPMC5004076 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Li Ping P Jia Yan-Fei YF Ma Xiao-Li XL Zheng Yan Y Kong Yi Y Zhang Yao Y Zong Shuai S Chen Zhi-Tao ZT Wang Yun-Shan YS
American journal of cancer research 20160801 8
Differentiated embryonic chondrocyte expressed gene 2 (DEC2; BHLHE41/Sharp1) is a helix-loop-helix (bHLH) transcription factor, and its deregulation has been observed in several tumors. However, this gene's effects on tumor progression are controversial, and its roles in gastric cancer (GC) remain unclear. In the present study, we found that DEC2 expression level is lower in GC tissues compared with adjacent non-tumor tissues, and negatively correlated with tumor invasion, lymph node metastasis, ...[more]