Ontology highlight
ABSTRACT:
SUBMITTER: Brown BC
PROVIDER: S-EPMC5005434 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Brown Brielin C BC Ye Chun Jimmie CJ Price Alkes L AL Zaitlen Noah N
American journal of human genetics 20160616 1
The increasing number of genetic association studies conducted in multiple populations provides an unprecedented opportunity to study how the genetic architecture of complex phenotypes varies between populations, a problem important for both medical and population genetics. Here, we have developed a method for estimating the transethnic genetic correlation: the correlation of causal-variant effect sizes at SNPs common in populations. This methods takes advantage of the entire spectrum of SNP ass ...[more]