Ontology highlight
ABSTRACT:
SUBMITTER: Huang F
PROVIDER: S-EPMC5005454 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Cell 20160707 4
Fluorescence nanoscopy, or super-resolution microscopy, has become an important tool in cell biological research. However, because of its usually inferior resolution in the depth direction (50-80 nm) and rapidly deteriorating resolution in thick samples, its practical biological application has been effectively limited to two dimensions and thin samples. Here, we present the development of whole-cell 4Pi single-molecule switching nanoscopy (W-4PiSMSN), an optical nanoscope that allows imaging of ...[more]