Can patients without early, prominent visual deficits still be diagnosed of posterior cortical atrophy?

ABSTRACT:

Background

Early and progressive disabling visual impairment is a core feature for the diagnosis of posterior cortical atrophy (PCA). However, some individuals that fulfil criteria over time might initially present with an onset of prominent posterior dysfunction other than visuoperceptual.

Methods

The clinical profile of five patients with a predominantly 'non-visual' posterior presentation (PCA2) was investigated and compared with sixteen individuals with visually predominant PCA (PCA1) and eighteen with typical amnestic Alzheimer disease (tAD).

Results

PCA2 patients showed significantly better performance than PCA1 in one visuospatial task and were free of Balint's syndrome and visual agnosia. Compared to tAD, PCA2 showed trends towards significantly lower performa

SUBMITTER: Suarez-Gonzalez A 

PROVIDER: S-EPMC5006821 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature