Phylogenomic analysis supports the ancestral presence of LPS-outer membranes in the Firmicutes.
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ABSTRACT:
SUBMITTER: Antunes LC
PROVIDER: S-EPMC5007114 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Publications
Phylogenomic analysis supports the ancestral presence of LPS-outer membranes in the Firmicutes.
Antunes Luisa Cs LC Poppleton Daniel D Klingl Andreas A Criscuolo Alexis A Dupuy Bruno B Brochier-Armanet Céline C Beloin Christophe C Gribaldo Simonetta S
eLife 20160831
One of the major unanswered questions in evolutionary biology is when and how the transition between diderm (two membranes) and monoderm (one membrane) cell envelopes occurred in Bacteria. The Negativicutes and the Halanaerobiales belong to the classically monoderm Firmicutes, but possess outer membranes with lipopolysaccharide (LPS-OM). Here, we show that they form two phylogenetically distinct lineages, each close to different monoderm relatives. In contrast, their core LPS biosynthesis enzyme ...[more]
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