Ontology highlight
ABSTRACT:
SUBMITTER: Yang J
PROVIDER: S-EPMC5007654 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Yang Jialiang J Huang Tao T Song Won-Min WM Petralia Francesca F Mobbs Charles V CV Zhang Bin B Zhao Yong Y Schadt Eric E EE Zhu Jun J Tu Zhidong Z
Scientific reports 20160901
Although our knowledge of aging has greatly expanded in the past decades, it remains elusive why and how aging contributes to the development of age-related diseases (ARDs). In particular, a global mechanistic understanding of the connections between aging and ARDs is yet to be established. We rely on a network modelling named "GeroNet" to study the connections between aging and more than a hundred diseases. By evaluating topological connections between aging genes and disease genes in over thre ...[more]