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Using photographic interpretation to evaluate the safety of home environments.

ABSTRACT: In the US there were 400,000 home fires resulting in 2755 deaths, 12,450 injuries, and $6.9B lost. The purpose of this study was to evaluate the content-validity of photographs taken in the home for use as an educational instrument to teach about "safe" and "unsafe" fire safety practice for adults and older adults. A total of 73 home fire safety experts were provided 27 photographs to evaluate home fire safety practice. Initially, a Krippendorff's alpha was calculated for the first 24 questions to evaluate inter-rater reliability, and differences in demographics were evaluated. Unique codes and themes for the last three questions were identified and inter-rater reliability examined. A majority of respondents were female (n = 43, 60.6%), college educated (n = 61, 83.6%), nurses (n = 25, 33.8%), or worked for a fire department (n = 21, 29.6%). Their mean age was 45.5 years and they had 11.05 years of experience. The first 24 questions had high inter-rater reliability (Krippendorff ? = 0.831). No significant differences existed between the strata of the demographic variables (all p-values > 0.05). Similarly, based on the codes and themes identified, the last three questions had moderate-to-good inter-rater reliability (Krippendorff ? = 0.764). Providing photographs as a 'seek-and-find' or 'What's wrong with this picture?' tools and simplified visual images is an excellent way to aid recognition of unsafe home fire safety environments. Education through non-traditional visual methods increases the possibility of change for diverse low-literacy populations.

SUBMITTER: Lehna C

PROVIDER: S-EPMC5008039 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature

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Using photographic interpretation to evaluate the safety of home environments.

Lehna Carlee C Twyman Stephanie S Myers John J

Preventive medicine reports 20160826

In the US there were 400,000 home fires resulting in 2755 deaths, 12,450 injuries, and $6.9B lost. The purpose of this study was to evaluate the content-validity of photographs taken in the home for use as an educational instrument to teach about "safe" and "unsafe" fire safety practice for adults and older adults. A total of 73 home fire safety experts were provided 27 photographs to evaluate home fire safety practice. Initially, a Krippendorff's alpha was calculated for the first 24 questions ...[more]

PMID: 27617192

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Project description:Current standards for safe delivery of electrical stimulation to the central nervous system are based on foundational studies which examined post-mortem tissue for histological signs of damage. This set of observations and the subsequently proposed limits to safe stimulation, termed the “Shannon limits,” allow for a simple calculation (using charge per phase and charge density) to determine the intensity of electrical stimulation that can be delivered safely to brain tissue. In the three decades since the Shannon limits were reported, advances in molecular biology have allowed for more nuanced and detailed approaches to be used to expand current understanding of the physiological effects of stimulation. Here, we investigated spatial transcriptomics as a new approach to assess the safety and efficacy of electrical stimulation in the brain. Electrical stimulation was delivered to the rat visual cortex with either acute or chronic electrode implantation procedures (acute: tissue collection 3 hours post-stimulation on the day of surgery; chronic: stimulation delivered 1-month post-implantation, and tissue collection 24 hours later). To explore the influence of device type and stimulation parameters, we used carbon fiber ultramicroelectrode arrays (7 µm diameter) and microwire electrode arrays (50 µm diameter) delivering charge and charge density levels selected above and below reported tissue damage thresholds (range: 2-20 nC, 0.1-1 mC/cm2). Spatial transcriptomics was performed using Visium Spatial Gene Expression Slides (10x Genomics), which enabled simultaneous immunohistochemistry and spatial transcriptomics to directly compare traditional histological metrics to transcriptional profiles within each tissue sample. Our data revealed unique spatial patterns of differentially expressed genes that are related to cellular processes including inflammation, cell cycle progression, and plasticity. Effects were dependent on stimulation parameters and were localized to both traditional and ultra-small device locations. The abundance of data gathered using this approach allows for sophisticated analysis that can be used to generate new hypotheses while also revealing novel potential biomarkers of neurostimulation.

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Using photographic interpretation to evaluate the safety of home environments.

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Using photographic interpretation to evaluate the safety of home environments.

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