Disrupted anatomic networks in the 22q11.2 deletion syndrome.
Ontology highlight
ABSTRACT:
SUBMITTER: Schmitt JE
PROVIDER: S-EPMC5008050 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
Disrupted anatomic networks in the 22q11.2 deletion syndrome.
Schmitt J Eric JE Yi James J Calkins Monica E ME Ruparel Kosha K Roalf David R DR Cassidy Amy A Souders Margaret C MC Satterthwaite Theodore D TD McDonald-McGinn Donna M DM Zackai Elaine H EH Gur Ruben C RC Emanuel Beverly S BS Gur Raquel E RE
NeuroImage. Clinical 20160825
The 22q11.2 deletion syndrome (22q11DS) is an uncommon genetic disorder with an increased risk of psychosis. Although the neural substrates of psychosis and schizophrenia are not well understood, aberrations in cortical networks represent intriguing potential mechanisms. Investigations of anatomic networks within 22q11DS are sparse. We investigated group differences in anatomic network structure in 48 individuals with 22q11DS and 370 typically developing controls by analyzing covariance patterns ...[more]
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