Neural Correlates and Connectivity Underlying Stress-Related Impulse Control Difficulties in Alcoholism.

ABSTRACT:

Background

Stress triggers impulsive and addictive behaviors, and alcoholism has been frequently associated with increased stress sensitivity and impulse control problems. However, neural correlates underlying the link between alcoholism and impulsivity in the context of stress in patients with alcohol use disorders (AUD) have not been well studied.

Methods

This study investigated neural correlates and connectivity patterns associated with impulse control difficulties in abstinent AUD patients. Using functional magnetic resonance imaging, brain responses of 37 AUD inpatients, and 37 demographically matched healthy controls were examined during brief individualized imagery trials of stress, alcohol cue, and neutral-relaxing conditions. Stress-related impulsivity was measured

SUBMITTER: Seo D 

PROVIDER: S-EPMC5008995 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature