Characteristics Predictive for a Successful Switch from Insulin Analogue Therapy to Oral Hypoglycemic Agents in Patients with Type 2 Diabetes.

ABSTRACT:

Purpose

The objective of this study was to investigate clinical and laboratory parameters that could predict which patients could maintain adequate glycemic control after switching from initial insulin therapy to oral hypoglycemic agents (OHAs) among patients with type 2 diabetes (T2D).

Materials and methods

We recruited 275 patients with T2D who had been registered in 3 cohorts of initiated insulin therapy and followed up for 33 months. The participants were divided into 2 groups according to whether they switched from insulin to OHAs (Group I) or not (Group II), and Group I was further classified into 2 sub-groups: maintenance on OHAs (Group IA) or resumption of insulin (Group IB).

Results

Of 275 patients with insulin initiation, 63% switched to OHAs (Group I) and 3

SUBMITTER: Kim G 

PROVIDER: S-EPMC5011271 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature