Ontology highlight
ABSTRACT:
SUBMITTER: Comptour A
PROVIDER: S-EPMC5011693 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Comptour Aurélie A Rouzaire Marion M Belville Corinne C Bonnin Nicolas N Daniel Estelle E Chiambaretta Frédéric F Blanchon Loïc L Sapin Vincent V
Scientific reports 20160906
Vitamin A and its active forms (retinoic acids/RAs) are known to have pro-healing properties, but their mechanisms of action are still poorly understood. This work aimed to identify the cellular and molecular processes by which atRA (all-trans RA) improves wound healing, using an in vivo model of mouse corneal alkali burns and an in vitro cellular human corneal epithelial injury model. Regulation by atRA has been studied on most of the cellular events that occur in wound healing. We investigated ...[more]