Ontology highlight
ABSTRACT:
SUBMITTER: Boudreault S
PROVIDER: S-EPMC5012649 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Boudreault Simon S Martenon-Brodeur Camille C Caron Marie M Garant Jean-Michel JM Tremblay Marie-Pier MP Armero Victoria E S VE Durand Mathieu M Lapointe Elvy E Thibault Philippe P Tremblay-Létourneau Maude M Perreault Jean-Pierre JP Scott Michelle S MS Lemay Guy G Bisaillon Martin M
PloS one 20160906 9
Alternative splicing (AS) is a central mechanism of genetic regulation which modifies the sequence of RNA transcripts in higher eukaryotes. AS has been shown to increase both the variability and diversity of the cellular proteome by changing the composition of resulting proteins through differential choice of exons to be included in mature mRNAs. In the present study, alterations to the global RNA splicing landscape of cellular genes upon viral infection were investigated using mammalian reoviru ...[more]