DyNet: visualization and analysis of dynamic molecular interaction networks.
Ontology highlight
ABSTRACT: Unlabelled
: The ability to experimentally determine molecular interactions on an almost proteome-wide scale under different conditions is enabling researchers to move from static to dynamic network analysis, uncovering new insights into how interaction networks are physically rewired in response to different stimuli and in disease. Dynamic interaction data presents a special challenge in network biology. Here, we present DyNet, a Cytoscape application that provides a range of functionalities for the visualization, real-time synchronization and analysis of large multi-state dynamic molecular interaction networks enabling users to quickly identify and analyze the most 'rewired' nodes across many network states.Availability and implementation
DyNet is available at the Cytoscape (3.2+) App Store (http://apps.cytoscape.org/apps/dynet).Contact
david.lynn@sahmri.comSupplementary information
Supplementary data are available at Bioinformatics online.
SUBMITTER: Goenawan IH
PROVIDER: S-EPMC5013899 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Publications
DyNet: visualization and analysis of dynamic molecular interaction networks.
Goenawan Ivan H IH Bryan Kenneth K Lynn David J DJ
Bioinformatics (Oxford, England) 20160503 17
<h4>Unlabelled</h4>: The ability to experimentally determine molecular interactions on an almost proteome-wide scale under different conditions is enabling researchers to move from static to dynamic network analysis, uncovering new insights into how interaction networks are physically rewired in response to different stimuli and in disease. Dynamic interaction data presents a special challenge in network biology. Here, we present DyNet, a Cytoscape application that provides a range of functional ...[more]
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