Ontology highlight
ABSTRACT:
SUBMITTER: Hou J
PROVIDER: S-EPMC5014955 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Hou Jingyi J Ouyang Yi Y Deng Haiquan H Chen Zhong Z Song Bin B Xie Zhongyu Z Wang Peng P Li Jinteng J Li Weiping W Yang Rui R
Stem cells international 20160825
Synovium-derived mesenchymal stromal cells (SMSCs) may play an important role in the pathogenesis of rheumatoid arthritis (RA) and show promise for therapeutic applications in RA. In this study, a whole-genome microarray analysis was used to detect differential gene expression in SMSCs from RA patients and healthy donors (HDs). Our results showed that there were 4828 differentially expressed genes in the RA group compared to the HD group; 3117 genes were upregulated, and 1711 genes were downregu ...[more]