Transcriptomic profiling of long non-coding RNAs in dermatomyositis by microarray analysis.
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ABSTRACT:
SUBMITTER: Peng QL
PROVIDER: S-EPMC5015085 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Publications
Transcriptomic profiling of long non-coding RNAs in dermatomyositis by microarray analysis.
Peng Qing-Lin QL Zhang Ya-Mei YM Yang Han-Bo HB Shu Xiao-Ming XM Lu Xin X Wang Guo-Chun GC
Scientific reports 20160908
Long non-coding RNAs (lncRNAs) are prevalently transcribed in the genome and have been found to be of functional importance. However, the potential roles of lncRNAs in dermatomyositis (DM) remain unknown. In this study, a lncRNA + mRNA microarray analysis was performed to profile lncRNAs and mRNAs from 15 treatment-naive DM patients and 5 healthy controls. We revealed a total of 1198 lncRNAs (322 up-regulated and 876 down-regulated) and 1213 mRNAs (665 up-regulated and 548 down-regulated) were s ...[more]
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