Ontology highlight
ABSTRACT:
SUBMITTER: Moaddel R
PROVIDER: S-EPMC5018564 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Moaddel Ruin R Fabbri Elisa E Khadeer Mohammed A MA Carlson Olga D OD Gonzalez-Freire Marta M Zhang Pingbo P Semba Richard D RD Ferrucci Luigi L
The journals of gerontology. Series A, Biological sciences and medical sciences 20160330 10
Aging is characterized by progressive decline in muscle mass, strength, and quality all of which contribute to functional impairment, falls, mobility disability, and frailty. Circulating factors may provide clues on the mechanisms for decline in muscle quality with aging. Characterizing the metabolic profile associated with reduced muscle quality in older persons could have important translational implications for the early identification of subjects at high risk of developing sarcopenia and the ...[more]