Effects of T208E activating mutation on MARK2 protein structure and dynamics: Modeling and simulation.
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ABSTRACT:
SUBMITTER: Ahrari S
PROVIDER: S-EPMC5019223 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
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Effects of T208E activating mutation on MARK2 protein structure and dynamics: Modeling and simulation.
Ahrari Sajjad S Mogharrab Navid N
Molecular biology research communications 20140901 3
Microtubule Affinity-Regulating Kinase 2 (MARK2) protein has a substantial role in regulation of vital cellular processes like induction of polarity, regulation of cell junctions, cytoskeleton structure and cell differentiation. The abnormal function of this protein has been associated with a number of pathological conditions like Alzheimer disease, autism, several carcinomas and development of virulent effects of <i>Helicobacter pylori</i>ββαβββ. ...[more]
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