Ontology highlight
ABSTRACT:
SUBMITTER: Bernardi L
PROVIDER: S-EPMC5019339 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Bernardi Livia L Frangipane Francesca F Smirne Nicoletta N Colao Rosanna R Puccio Gianfranco G Curcio Sabrina Am SA Mirabelli Maria M Maletta Raffaele R Anfossi Maria M Gallo Maura M Geracitano Silvana S Conidi Maria Elena ME Di Lorenzo Raffale R Clodomiro Alessandra A Cupidi Chiara C Marzano Sandra S Comito Francesco F Valenti Vincenzo V Zirilli Maria Angela MA Ghani Mahdi M Xi Zhengrui Z Sato Christine C Moreno Danielle D Borelli Annelisa A Leone Rosa Anna RA St George-Hyslop Peter P Rogaeva Ekaterina E Bruni Amalia C AC
Neurobiology of aging 20120720 12
The objectives of this study were to estimate frontotemporal dementia (FTD) prevalence, identify FTD-related mutations, and correlate FTD phenotype with mutations in a southern Italian population. The study population consisted of subjects ≥ 50 years of age residing in the Community of Biv. on January 1, 2004, and a door-to-door 2-phase design was used. Genetic and biochemical analyses were done on samples collected from 32 patients. Prevalence rates were 0.6 for Alzheimer's disease, 0.4 for vas ...[more]