Ontology highlight
ABSTRACT:
SUBMITTER: Overton ET
PROVIDER: S-EPMC5020348 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Overton Edgar Turner ET Tebas Pablo P Coate Bruce B Ryan Robert R Perniciaro Amy A Dayaram Yaswant K YK De La Rosa Guy G Baugh Bryan P BP
HIV clinical trials 20160301 2
<h4>Background</h4>The phase 4, METABOLIK trial demonstrated that changes in metabolic parameters with darunavir with low-dose ritonavir (DRV/r) were comparable to those observed with atazanavir with low-dose ritonavir (ATV/r). A comprehensive assessment of the effects of these agents on insulin sensitivity will provide additional, relevant clinical information.<h4>Methods</h4>In this substudy of METABOLIK, HIV-1-infected, antiretroviral agent-naïve male subjects aged ≥18 years with a viral load ...[more]