Ontology highlight
ABSTRACT:
SUBMITTER: Westfall MV
PROVIDER: S-EPMC5021686 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Frontiers in physiology 20160914
Secondary shifts develop in post-translational phosphorylation of sarcomeric proteins in multiple animal models of inherited cardiomyopathy. These signaling alterations together with the primary mutation are predicted to contribute to the overall cardiac phenotype. As a result, identification and integration of post-translational myofilament signaling responses are identified as priorities for gaining insights into sarcomeric cardiomyopathies. However, significant questions remain about the natu ...[more]