Ontology highlight
ABSTRACT:
SUBMITTER: Haftchenary S
PROVIDER: S-EPMC5022782 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Haftchenary Sina S Nelson Shawn D SD Furst Laura L Dandapani Sivaraman S Ferrara Steven J SJ Bošković Žarko V ŽV Figueroa Lazú Samuel S Guerrero Adrian M AM Serrano Juan C JC Crews DeMarcus K DK Brackeen Cristina C Mowat Jeffrey J Brumby Thomas T Bauser Marcus M Schreiber Stuart L SL Phillips Andrew J AJ
ACS combinatorial science 20160812 9
Efficient syntheses of chiral fragments derived from chiral amino alcohols are described. Several unique scaffolds were readily accessed in 1-5 synthetic steps leading to 45 chiral fragments, including oxazolidinones, morpholinones, lactams, and sultams. These fragments have molecular weights ranging from 100 to 255 Da and are soluble in water (0.085 to >15 mM). ...[more]