Ontology highlight
ABSTRACT:
SUBMITTER: Vermunt MW
PROVIDER: S-EPMC5023742 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Vermunt Marit W MW Creyghton Menno P MP
Current neurology and neuroscience reports 20161001 10
Over the last decade, the noncoding part of the genome has been shown to harbour thousands of cis-regulatory elements, such as enhancers, that activate well-defined gene expression programs. Driven by the development of numerous techniques, many of these elements are now identified in multiple tissues and cell types, and their characteristics as well as importance in development and disease are becoming increasingly clear. Here, we provide an overview of the insights that were gained from the an ...[more]