Ontology highlight
ABSTRACT:
SUBMITTER: Boritsch EC
PROVIDER: S-EPMC5024641 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Boritsch Eva C EC Khanna Varun V Pawlik Alexandre A Honoré Nadine N Navas Victor H VH Ma Laurence L Bouchier Christiane C Seemann Torsten T Supply Philip P Stinear Timothy P TP Brosch Roland R
Proceedings of the National Academy of Sciences of the United States of America 20160815 35
Horizontal gene transfer (HGT) is a major driving force of bacterial diversification and evolution. For tuberculosis-causing mycobacteria, the impact of HGT in the emergence and distribution of dominant lineages remains a matter of debate. Here, by using fluorescence-assisted mating assays and whole genome sequencing, we present unique experimental evidence of chromosomal DNA transfer between tubercle bacilli of the early-branching Mycobacterium canettii clade. We found that the obtained recombi ...[more]