Ontology highlight
ABSTRACT:
SUBMITTER: Cao Z
PROVIDER: S-EPMC5025752 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Scientific reports 20160916
To investigate the commonalities and specificities across tumor lineages, we perform a systematic pan-cancer transcriptomic study across 6744 specimens. We find six pan-cancer subnetwork signatures which relate to cell cycle, immune response, Sp1 regulation, collagen, muscle system and angiogenesis. Moreover, four pan-cancer subnetwork signatures demonstrate strong prognostic potential. We also characterize 16 cancer type-specific subnetwork signatures which show diverse implications to somatic ...[more]