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Mapping Phylogenetic Trees to Reveal Distinct Patterns of Evolution.

ABSTRACT:

Unlabelled

Evolutionary relationships are frequently described by phylogenetic trees, but a central barrier in many fields is the difficulty of interpreting data containing conflicting phylogenetic signals. We present a metric-based method for comparing trees which extracts distinct alternative evolutionary relationships embedded in data. We demonstrate detection and resolution of phylogenetic uncertainty in a recent study of anole lizards, leading to alternate hypotheses about their evolutionary relationships. We use our approach to compare trees derived from different genes of Ebolavirus and find that the VP30 gene has a distinct phylogenetic signature composed of three alternatives that differ in the deep branching structure.

Key words

phylogenetics, evolution, tree metrics, genetics, sequencing.

SUBMITTER: Kendall M

PROVIDER: S-EPMC5026250 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature

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Mapping Phylogenetic Trees to Reveal Distinct Patterns of Evolution.

Kendall Michelle M Colijn Caroline C

Molecular biology and evolution 20160624 10

<h4>Unlabelled</h4>Evolutionary relationships are frequently described by phylogenetic trees, but a central barrier in many fields is the difficulty of interpreting data containing conflicting phylogenetic signals. We present a metric-based method for comparing trees which extracts distinct alternative evolutionary relationships embedded in data. We demonstrate detection and resolution of phylogenetic uncertainty in a recent study of anole lizards, leading to alternate hypotheses about their evo ...[more]

PMID: 27343287

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