Ontology highlight
ABSTRACT:
SUBMITTER: Gao JH
PROVIDER: S-EPMC5026725 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Gao Jin-Hang JH Wen Shi-Lei SL Feng Shi S Yang Wen-Juan WJ Lu Yao-Yao YY Tong Huan H Liu Rui R Tang Shi-Hang SH Huang Zhi-Yin ZY Tang Ying-Mei YM Yang Jin-Hui JH Xie Hui-Qi HQ Tang Cheng-Wei CW
Angiogenesis 20160705 4
Abnormal angiogenesis is critical for portal hypertension in cirrhosis. Except for etiological treatment, no efficient medication or regime has been explored to treat the early stage of cirrhosis when angiogenesis is initiated or overwhelming. In this study, we explored an anti-angiogenesis effort through non-cytotoxic drugs octreotide and celecoxib to treat early stage of cirrhotic portal hypertension in an animal model. Peritoneal injection of thioacetamide (TAA) was employed to induce liver c ...[more]