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Self-assembly of fully addressable DNA nanostructures from double crossover tiles.

ABSTRACT: DNA origami and single-stranded tile (SST) are two proven approaches to self-assemble finite-size complex DNA nanostructures. The construction elements appeared in structures from these two methods can also be found in multi-stranded DNA tiles such as double crossover tiles. Here we report the design and observation of four types of finite-size lattices with four different double crossover tiles, respectively, which, we believe, in terms of both complexity and robustness, will be rival to DNA origami and SST structures.

SUBMITTER: Wang W

PROVIDER: S-EPMC5027514 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature

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Self-assembly of fully addressable DNA nanostructures from double crossover tiles.

Wang Wen W Lin Tong T Zhang Suoyu S Bai Tanxi T Mi Yongli Y Wei Bryan B

Nucleic acids research 20160802 16

DNA origami and single-stranded tile (SST) are two proven approaches to self-assemble finite-size complex DNA nanostructures. The construction elements appeared in structures from these two methods can also be found in multi-stranded DNA tiles such as double crossover tiles. Here we report the design and observation of four types of finite-size lattices with four different double crossover tiles, respectively, which, we believe, in terms of both complexity and robustness, will be rival to DNA or ...[more]

PMID: 27484479

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