Ontology highlight
ABSTRACT:
SUBMITTER: Jo YS
PROVIDER: S-EPMC5028001 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Jo Yong Sang YS Mizumori Sheri J Y SJY
Cerebral cortex (New York, N.Y. : 1991) 20150922 10
Growing evidence indicates that midbrain dopamine (DA) cells integrate reward expectancy-related information from the prefrontal cortex to properly compute errors in reward prediction. Here we investigated how 2 major prefrontal subregions, the orbitofrontal cortex (OFC) and the medial prefrontal cortex (mPFC), contributed to DAergic prediction errors while rats performed a delay discounting task on a T-maze. Most putative DA cells in the task showed phasic responses to salient cues that predict ...[more]