Ontology highlight
ABSTRACT:
SUBMITTER: Lum SH
PROVIDER: S-EPMC5028092 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Drug design, development and therapy 20160913
Aplastic anemia (AA) is a potential life-threatening hematopoietic stem cell (HSC) disorder resulting in cytopenia. The mainstays of treatment for AA are definitive therapy to restore HSCs and supportive measures to ameliorate cytopenia-related complications. The standard definitive therapy is HSC transplantation for young and medically fit patients with suitable donors and immunosuppressive therapy (IST) with antithymocyte globulin and cyclosporine for the remaining patients. A significant prop ...[more]