Ontology highlight
ABSTRACT:
SUBMITTER: Volmering S
PROVIDER: S-EPMC5030078 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Volmering Stephanie S Block Helena H Boras Mark M Lowell Clifford A CA Zarbock Alexander A
Immunity 20160105 1
Neutrophils are recruited from the blood to sites of sterile inflammation, where they are involved in wound healing but can also cause tissue damage. During sterile inflammation, necrotic cells release pro-inflammatory molecules including formylated peptides. However, the signaling pathway triggered by formylated peptides to integrin activation and leukocyte recruitment is unknown. By using spinning-disk confocal intravital microscopy, we examined the molecular mechanisms of leukocyte recruitmen ...[more]