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Aflibercept for neovascular age-related macular degeneration.


ABSTRACT:

SUBMITTER: Sarwar S 

PROVIDER: S-EPMC5030844 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature

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<h4>Background</h4>Central vision loss caused by age-related macular degeneration (AMD) is the leading cause of blindness among the elderly in developed countries. Neovascular AMD is characterized by choroidal neovascularization (CNV). Growth of new blood vessels in patients with neovascular AMD is driven by a complex process that involves a signal protein called vascular endothelial growth factor A (VEGF-A). Anti-VEGF drugs that block this protein include ranibizumab, bevacizumab, and afliberce  ...[more]

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