Ontology highlight
ABSTRACT:
SUBMITTER: Yuan L
PROVIDER: S-EPMC5032117 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Yuan Lamei L Song Zhi Z Deng Xiong X Zheng Wen W Guo Yi Y Yang Zhijian Z Deng Hao H
Scientific reports 20160922
Parkinson's disease (PD) is one of the most common neurodegenerative disorders. Accumulated evidence confirms that genetic factors play a considerable role in PD pathogenesis. To examine whether point variants or haplotypes are associated with PD development, genotyping of 35 variants in 22 PD-related genes was performed in a well-characterized cohort of 512 Han Chinese PD patients and 512 normal controls. Both Pearson's χ<sup>2</sup> test and haplotype analysis were used to evaluate whether var ...[more]