Microvascular resistance of the culprit coronary artery in acute ST-elevation myocardial infarction.

ABSTRACT:

Background

Failed myocardial reperfusion is common and prognostically important after acute ST-elevation myocardial infarction (STEMI). The purpose of this study was to investigate coronary flow reserve (CFR), a measure of vasodilator capacity, and the index of microvascular resistance (IMR; mmHg × s) in the culprit artery of STEMI survivors.

Methods

IMR (n = 288) and CFR (n = 283; mean age [SD], 60 [12] years) were measured acutely using guide wire-based thermodilution. Cardiac MRI disclosed left ventricular pathology, function, and volumes at 2 days (n = 281) and 6 months after STEMI (n = 264). All-cause death or first heart failure hospitalization was independently adjudicated (median follow-up 845 days).

Results

Myocardial hemorrhage an

SUBMITTER: Carrick D 

PROVIDER: S-EPMC5033815 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature