Association of thrombophilia and catheter-associated thrombosis in children: a systematic review and meta-analysis.

ABSTRACT:

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Essentials It is unclear if thrombophilia increases the risk of catheter-associated thrombosis in children. We conducted a meta-analysis on thrombophilia and pediatric catheter-associated thrombosis. Presence of ≥1 trait confers additional risk of venous thrombosis in children with catheters. Limitations of included studies preclude us from recommending routine thrombophilia testing.

Summary

Background The association between thrombophilia and deep vein thrombosis (DVT) associated with central venous catheter (CVC) use, the most important pediatric risk factor for thrombosis, is unclear in children. Pediatric studies with small sample sizes have reported conflicting results. We sought to evaluate whether, among children with CVCs, thrombophilia increases the risk

SUBMITTER: Neshat-Vahid S 

PROVIDER: S-EPMC5035642 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature