Ontology highlight
ABSTRACT:
SUBMITTER: D' Amora M
PROVIDER: S-EPMC5037369 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
D' Amora Marta M Rodio Marina M Bartelmess Juergen J Sancataldo Giuseppe G Brescia Rosaria R Cella Zanacchi Francesca F Diaspro Alberto A Giordani Silvia S
Scientific reports 20160927
Functionalized carbon nano-onions (f-CNOs) are of great interest as platforms for imaging, diagnostic and therapeutic applications due to their high cellular uptake and low cytotoxicity. To date, the toxicological effects of f-CNOs on vertebrates have not been reported. In this study, the possible biological impact of f-CNOs on zebrafish during development is investigated, evaluating different toxicity end-points such as the survival rate, hatching rate, and heart beat rate. Furthermore, a bio-d ...[more]