Ontology highlight
ABSTRACT:
SUBMITTER: West JA
PROVIDER: S-EPMC5037409 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
West Jason A JA Mito Mari M Kurosaka Satoshi S Takumi Toru T Tanegashima Chiharu C Chujo Takeshi T Yanaka Kaori K Kingston Robert E RE Hirose Tetsuro T Bond Charles C Fox Archa A Nakagawa Shinichi S Nakagawa Shinichi S
The Journal of cell biology 20160919 7
Paraspeckles are nuclear bodies built on the long noncoding RNA Neat1, which regulates a variety of physiological processes including cancer progression and corpus luteum formation. To obtain further insight into the molecular basis of the function of paraspeckles, we performed fine structural analyses of these nuclear bodies using structural illumination microscopy. Notably, paraspeckle proteins are found within different layers along the radially arranged bundles of Neat1 transcripts, forming ...[more]