Ontology highlight
ABSTRACT:
SUBMITTER: Lorente L
PROVIDER: S-EPMC5037799 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Lorente Leonardo L Rodriguez Sergio T ST Sanz Pablo P Pérez-Cejas Antonia A Padilla Javier J Díaz Dácil D González Antonio A Martín María M MM Jiménez Alejandro A Barrera Manuel A MA
International journal of molecular sciences 20160909 9
Cytokeratin (CK)-18 is the major intermediate filament protein in the liver and during hepatocyte apoptosis is cleaved by the action of caspases; the resulting fragments are released into the blood as caspase-cleaved cytokeratin (CCCK)-18. Higher circulating levels of CCCK-18 have been found in patients with hepatocellular carcinoma (HCC) than in healthy controls and than in cirrhotic patients. However, it is unknown whether serum CCCK-18 levels before liver transplantation (LT) in patients with ...[more]