Ontology highlight
ABSTRACT:
SUBMITTER: Mourand G
PROVIDER: S-EPMC5038322 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Antimicrobial agents and chemotherapy 20160923 10
Resistance to extended-spectrum cephalosporins (ESCs) is a matter of considerable concern for public health. Here, we studied the spontaneous loss of an extended-spectrum beta-lactamase (ESBL)-encoding plasmid from a rifampin-resistant Escherichia coli isolate orally inoculated into pigs under controlled conditions. Fecal samples were collected and cultured on rifampin-supplemented medium, and the resistance of the E. coli isolates to ESCs was studied by phenotypic tests, PCR detection of plasmi ...[more]