Ontology highlight
ABSTRACT:
SUBMITTER: Loraine J
PROVIDER: S-EPMC5038329 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Loraine Jessica J Pu Feifei F Turapov Obolbek O Mukamolova Galina V GV
Antimicrobial agents and chemotherapy 20160923 10
Tuberculosis is a major infectious disease that requires prolonged chemotherapy with a combination of four drugs. Here we present data suggesting that treatment of Mycobacterium tuberculosis, the causative agent of tuberculosis, and Mycobacterium smegmatis, a model organism widely used for the screening of antituberculosis agents, with first-line drugs resulted in the generation of substantial populations that could be recovered only by the addition of a culture supernatant from growing mycobact ...[more]