Emerging role of microRNA-21 in cancer.
Ontology highlight
ABSTRACT:
SUBMITTER: Feng YH
PROVIDER: S-EPMC5038362 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Publications
Emerging role of microRNA-21 in cancer.
Feng Yin-Hsun YH Tsao Chao-Jung CJ
Biomedical reports 20160826 4
MicroRNAs (miRs) are a class of single-stranded RNA molecules of 15-27 nucleotides in length that regulate gene expression at the post-translational level. miR-21 is one of the earliest identified cancer-promoting 'oncomiRs', targeting numerous tumor suppressor genes associated with proliferation, apoptosis and invasion. The regulation of miR-21 and its role in carcinogenesis have been extensively investigated. Recent studies have focused on the diagnostic and prognostic value of miR-21 as well ...[more]
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