Browse
Submit Data
Databases
API
Help

Dataset Information

21 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Resonance Frequency of Optical Microbubble Resonators: Direct Measurements and Mitigation of Fluctuations.

ABSTRACT: This work shows the improvements in the sensing capabilities and precision of an Optical Microbubble Resonator due to the introduction of an encaging poly(methyl methacrylate) (PMMA) box. A frequency fluctuation parameter ? was defined as a score of resonance stability and was evaluated in the presence and absence of the encaging system and in the case of air- or water-filling of the cavity. Furthermore, the noise interference introduced by the peristaltic and the syringe pumping system was studied. The measurements showed a reduction of ? in the presence of the encaging PMMA box and when the syringe pump was used as flowing system.

SUBMITTER: Cosci A

PROVIDER: S-EPMC5038683 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Publications

Resonance Frequency of Optical Microbubble Resonators: Direct Measurements and Mitigation of Fluctuations.

Cosci Alessandro A Berneschi Simone S Giannetti Ambra A Farnesi Daniele D Cosi Franco F Baldini Francesco F Nunzi Conti Gualtiero G Soria Silvia S Barucci Andrea A Righini Giancarlo G Pelli Stefano S

Sensors (Basel, Switzerland) 20160831 9

This work shows the improvements in the sensing capabilities and precision of an Optical Microbubble Resonator due to the introduction of an encaging poly(methyl methacrylate) (PMMA) box. A frequency fluctuation parameter σ was defined as a score of resonance stability and was evaluated in the presence and absence of the encaging system and in the case of air- or water-filling of the cavity. Furthermore, the noise interference introduced by the peristaltic and the syringe pumping system was stud ...[more]

PMID: 27589761

Similar Datasets

Microbubble Resonators for All-Optical Photoacoustics of Flowing Contrast Agents.

Project description:In this paper, we implement a Whispering Gallery mode microbubble resonator (MBR) as an optical transducer to detect the photoacoustic (PA) signal generated by plasmonic nanoparticles. We simulate a flow cytometry experiment by letting the nanoparticles run through the MBR during measurements and we estimate PA intensity by a Fourier analysis of the read-out signal. This method exploits the peaks associated with the MBR mechanical eigenmodes, allowing the PA response of the nanoparticles to be decoupled from the noise associated with the particle flow whilst also increasing the signal-to-noise ratio. The photostability curve of a known contrast agent is correctly reconstructed, validating the proposed analysis and proving quantitative PA detection. The experiment was run to demonstrate the feasible implementation of the MBR system in a flow cytometry application (e.g., the detection of venous thrombi or circulating tumor cells), particularly regarding wearable appliances. Indeed, these devices could also benefit from other MBR features, such as the extreme compactness, the direct implementation in a microfluidic circuit, and the absence of impedance-matching material.

| S-EPMC7175143 | biostudies-literature

Gain-through-filtering enables tuneable frequency comb generation in passive optical resonators.

Project description:Optical frequency combs (OFCs), consisting of a set of phase-locked, equally spaced laser frequency lines, have enabled a great leap in precision spectroscopy and metrology since seminal works of Hänsch et al. Nowadays, OFCs are cornerstones of a wealth of further applications ranging from chemistry and biology to astrophysics and including molecular fingerprinting and light detection and ranging (LIDAR) systems, among others. Driven passive optical resonators constitute the ideal platform for OFC generation in terms of compactness and low energy footprint. We propose here a technique for the generation of OFCs with a tuneable repetition rate in externally driven optical resonators based on the gain-through-filtering process, a simple and elegant method, due to asymmetric spectral filtering on one side of the pump wave. We demonstrate a proof-of-concept experimental result in a fibre resonator, pioneering a new technique that does not require specific engineering of the resonator dispersion to generate frequency-agile OFCs.

| S-EPMC6776525 | biostudies-literature

Ultrasensitive Detection of Human Chorionic Gonadotropin Using Frequency Locked Microtoroid Optical Resonators.

Project description:Clean sport competition is of significant concern to many governments and sporting organizations. Highly sensitive and rapid sensors are needed to improve the detection of performance enhancing drugs in sports as athletes take diuretics to dilute the concentration of drugs in their urine and microdose under the detectable limits of current sensors. Here we demonstrate, using frequency locked microtoroid optical resonators, a 3 orders of magnitude improvement in detection limit over the current gold standard, mass spectrometry, for the common performance enhancing drug, human chorionic gonadotropin (hCG). hCG, also known as the pregnancy hormone, was detected both in simulated urine and in the urine of pregnant donors at a concentration of 1 and 3 femtomolar, respectively. We anticipate that the sensitivity provided by frequency locked optical microcavities can enable a new standard in antidoping research.

| S-EPMC6991119 | biostudies-literature

Anomalous time delays and quantum weak measurements in optical micro-resonators.

Project description:Quantum weak measurements, wavepacket shifts and optical vortices are universal wave phenomena, which originate from fine interference of multiple plane waves. These effects have attracted considerable attention in both classical and quantum wave systems. Here we report on a phenomenon that brings together all the above topics in a simple one-dimensional scalar wave system. We consider inelastic scattering of Gaussian wave packets with parameters close to a zero of the complex scattering coefficient. We demonstrate that the scattered wave packets experience anomalously large time and frequency shifts in such near-zero scattering. These shifts reveal close analogies with the Goos-Hänchen beam shifts and quantum weak measurements of the momentum in a vortex wavefunction. We verify our general theory by an optical experiment using the near-zero transmission (near-critical coupling) of Gaussian pulses propagating through a nano-fibre with a side-coupled toroidal micro-resonator. Measurements demonstrate the amplification of the time delays from the typical inverse-resonator-linewidth scale to the pulse-duration scale.

| S-EPMC5476806 | biostudies-other

Force spectroscopy with dual-trap optical tweezers: molecular stiffness measurements and coupled fluctuations analysis.

Project description:Dual-trap optical tweezers are often used in high-resolution measurements in single-molecule biophysics. Such measurements can be hindered by the presence of extraneous noise sources, the most prominent of which is the coupling of fluctuations along different spatial directions, which may affect any optical tweezers setup. In this article, we analyze, both from the theoretical and the experimental points of view, the most common source for these couplings in dual-trap optical-tweezers setups: the misalignment of traps and tether. We give criteria to distinguish different kinds of misalignment, to estimate their quantitative relevance and to include them in the data analysis. The experimental data is obtained in a, to our knowledge, novel dual-trap optical-tweezers setup that directly measures forces. In the case in which misalignment is negligible, we provide a method to measure the stiffness of traps and tether based on variance analysis. This method can be seen as a calibration technique valid beyond the linear trap region. Our analysis is then employed to measure the persistence length of dsDNA tethers of three different lengths spanning two orders of magnitude. The effective persistence length of such tethers is shown to decrease with the contour length, in accordance with previous studies.

| S-EPMC3491705 | biostudies-literature

Frequency-noise measurements of optical frequency combs by multiple fringe-side discriminator.

Project description:The frequency noise of an optical frequency comb is routinely measured through the hetherodyne beat of one comb tooth against a stable continuous-wave laser. After frequency-to-voltage conversion, the beatnote is sent to a spectrum analyzer to retrive the power spectral density of the frequency noise. Because narrow-linewidth continuous-wave lasers are available only at certain wavelengths, heterodyning the comb tooth can be challenging. We present a new technique for direct characterization of the frequency noise of an optical frequency comb, requiring no supplementary reference lasers and easily applicable in all spectral regions from the terahertz to the ultraviolet. The technique is based on the combination of a low finesse Fabry-Perot resonator and the so-called "fringe-side locking" method, usually adopted to characterize the spectral purity of single-frequency lasers, here generalized to optical frequency combs. The effectiveness of this technique is demonstrated with an Er-fiber comb source across the wavelength range from 1 to 2 μm.

| S-EPMC4637836 | biostudies-other

Optical Transduction for Vertical Nanowire Resonators.

Project description:We describe an optical transduction mechanism to measure the flexural mode vibrations of vertically aligned nanowires on a flat substrate with high sensitivity, linearity, and ease of implementation. We demonstrate that the light reflected from the substrate when a laser beam strikes it parallel to the nanowires is modulated proportionally to their vibration, so that measuring such modulation provides a highly efficient resonance readout. This mechanism is applicable to single nanowires or arrays without specific requirements regarding their geometry or array pattern, and no fabrication process besides the nanowire generation is required. We show how to optimize the performance of this mechanism by characterizing the split flexural modes of vertical silicon nanowires in their full dynamic range and up to the fifth mode order. The presented transduction approach is relevant for any application of nanowire resonators, particularly for integrating nanomechanical sensing in functional substrates based on vertical nanowires for biological applications.

| S-EPMC7146857 | biostudies-literature

Radio frequency spectral characterization and model parameters extraction of high Q optical resonators.

Project description:A microwave domain characterization approach is proposed to determine the properties of high quality factor optical resonators. This approach features a very high precision in frequency and aims to acquire a full knowledge of the complex transfer function (amplitude and phase) characterizing an optical resonator using a microwave vector network analyzer. It is able to discriminate between the different coupling regimes, from the under-coupling to the selective amplification, and it is used together with a model from which the main resonator parameters are extracted, i.e. coupling factor, intrinsic losses, phase slope, intrinsic and external quality factor.

| S-EPMC4890176 | biostudies-other

Chirped dissipative solitons in driven optical resonators.

Project description:Solitons are self-sustaining particle-like wave packets found throughout nature. Optical systems such as optical fibers and mode-locked lasers are relatively simple, are technologically important, and continue to play a major role in our understanding of the rich nonlinear dynamics of solitons. Here we present theoretical and experimental observations of a new class of optical soliton characterized by pulses with large and positive chirp in normal dispersion resonators with strong spectral filtering. Numerical simulations reveal several stable waveforms including dissipative solitons characterized by large frequency chirp. In experiments with fiber cavities driven with nanosecond pulses, chirped dissipative solitons matching predictions are observed. Remarkably, chirped pulses remain stable in low quality-factor resonators despite large dissipation, which enables new opportunities for nonlinear pattern formation. By extending pulse generation to normal dispersion systems and supporting higher pulse energies, chirped dissipative solitons will enable ultrashort pulse and frequency comb sources that are simpler and more effective for spectroscopy, communications, and metrology. Scaling laws are derived to provide simple design guidelines for generating chirped dissipative solitons in microresonator, fiber resonator, and bulk enhancement cavity platforms.

| S-EPMC8425384 | biostudies-literature

Optical wireless information transfer with nonlinear micromechanical resonators.

Project description:Wireless transfer of information is the basis of modern communication. It includes cellular, WiFi, Bluetooth, and GPS systems, all of which use electromagnetic radio waves with frequencies ranging from typically 100 MHz to a few GHz. However, several long-standing challenges with standard radio-wave wireless transmission still exist, including keeping secure transmission of data from potential compromise. Here, we demonstrate wireless information transfer using a line-of-sight optical architecture with a micromechanical element. In this fundamentally new approach, a laser beam encoded with information impinges on a nonlinear micromechanical resonator located a distance from the laser. The force generated by the radiation pressure of the laser light on the nonlinear micromechanical resonator produces a sideband modulation signal, which carries the precise information encoded in the subtle changes in the radiation pressure. Using this, we demonstrate data and image transfer with one hundred percent fidelity with a single 96-by-270 μm silicon resonator element in an optical frequency band. This mechanical approach relies only on the momentum of the incident photons and is therefore able to use any portion of the optical frequency band-a band that is 10 000 times wider than the radio frequency band. Our line-of-sight architecture using highly scalable micromechanical resonators offers new possibilities in wireless communication. Due to their small size, these resonators can be easily arrayed while maintaining a small form factor to provide redundancy and parallelism.

| S-EPMC6444992 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data