Ontology highlight
ABSTRACT:
SUBMITTER: Schafer R
PROVIDER: S-EPMC5040900 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Schäfer Richard R Spohn Gabriele G Baer Patrick C PC
Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie 20160720 4
Mesenchymal stem/stromal cells (MSCs) are becoming increasingly important for the development of cell therapeutics in regenerative medicine. Featuring immunomodulatory potential as well as secreting a variety of trophic factors, MSCs showed remarkable therapeutic effects in numerous preclinical disease models. However, sustainable translation of MSC therapies to the clinic is hampered by heterogeneity of MSCs and non-standardized in vitro culture technologies. Moreover, potent MSC therapeutics r ...[more]