NMR Chemical Shift Ranges of Urine Metabolites in Various Organic Solvents.
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ABSTRACT:
SUBMITTER: Gorling B
PROVIDER: S-EPMC5041126 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Publications
NMR Chemical Shift Ranges of Urine Metabolites in Various Organic Solvents.
Görling Benjamin B Bräse Stefan S Luy Burkhard B
Metabolites 20160902 3
Signal stability is essential for reliable multivariate data analysis. Urine samples show strong variance in signal positions due to inter patient differences. Here we study the exchange of the solvent of a defined urine matrix and how it affects signal and integral stability of the urinary metabolites by NMR spectroscopy. The exchange solvents were methanol, acetonitrile, dimethyl sulfoxide, chloroform, acetone, dichloromethane, and dimethyl formamide. Some of these solvents showed promising re ...[more]
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