Ontology highlight
ABSTRACT:
SUBMITTER: Rajkumar AS
PROVIDER: S-EPMC5041464 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Rajkumar Arun S AS Liu Guodong G Bergenholm David D Arsovska Dushica D Kristensen Mette M Nielsen Jens J Jensen Michael K MK Keasling Jay D JD
Nucleic acids research 20160620 17
Advances in synthetic biology and our understanding of the rules of promoter architecture have led to the development of diverse synthetic constitutive and inducible promoters in eukaryotes and prokaryotes. However, the design of promoters inducible by specific endogenous or environmental conditions is still rarely undertaken. In this study, we engineered and characterized a set of strong, synthetic promoters for budding yeast Saccharomyces cerevisiae that are inducible under acidic conditions ( ...[more]